Tephine 200 Microgram Sublingual Tablets

What Tephine is and what it is used for

Tephine is a strong painkiller that belongs to a group of medicines called opioids.

It is used to treat:

• severe pain, such as pain following surgery or injury, in heart attacks and in cancer.

Tephine is not used to treat headache, toothache, migraine or other pains treatable with weaker painkillers and/or medicines that relieve spasms.

Before you take Tephine:

Do not take Tephine

if you are/have

•    allergic (hypersensitive) to:

–    buprenorphine or other painkillers acting in the brain or spinal cord

–    any of the other ingredients of this medicine.

•    dependent on opioids or for withdrawal treatment from opioids.

•    serious breathing problems.

•    a serious liver disease.

•    treated or have been treated in the previous 2 weeks with medicines known as monoamine oxidase inhibitors, such as moclobemide.

These types of medicines are used to treat depression or Parkinson’s disease.

Taking Tephine with food and drink

Avoid drinking alcohol or taking any medicines that contain alcohol while taking Tephine.

How to take Tephine

Always take Tephine exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

The usual dose is:

•    Patients weighing more than 45 kg

Tephine 200 microgram

–    1-2 tablets as single dose

–    If necessary, 1-2 further tablets can be taken every 6-8 hours.

The dosage interval must be determined by the doctor, based upon observation of the individual patient.

Instruction for use Remove the sublingual tablets from the blister by pressing down on the whole tablet, so you need the least effort and you prevent the tablets from being crushed.

Method of use

The tablets are described as “sublingual”. This means that the tablet should be placed under the tongue and kept there until fully dissolved. This usually takes 5 to 10 minutes.

In the presence of very dry oral mucosa, a few drops of liquid will accelerate the dissolution process.

Do not suck, chew or swallow the tablets whole – the medicine will not work this way. Do not take the tablets at the same time as food or drink.

What Tephine contains:

•    The active substance is buprenorphine as

buprenorphine hydrochloride.

Tephine 200 microgram Sublingual Tablets

Each tablet contains 200 microgram buprenorphine.